Valentyn Oksenych Selected Research

O- (5- O- (4- coumaroyl)- alpha- arabinofuranosyl)- (1- 3)- O- beta- xylopyranosyl- (1- 4)- xylopyranose

12/2020	Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI.
1/2019	Synthetic lethality between DNA repair factors Xlf and Paxx is rescued by inactivation of Trp53.
1/2018	Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF.
1/2017	Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70.

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Valentyn Oksenych Research Topics

Disease

10	COVID-19 02/2024 - 01/2020
5	Ataxia Telangiectasia (Louis Bar Syndrome) 12/2019 - 01/2011
5	Genomic Instability 01/2019 - 02/2012
4	Virus Diseases (Viral Diseases) 11/2022 - 01/2018
3	Type 2 Diabetes Mellitus (MODY) 02/2024 - 01/2022
3	Infections 12/2023 - 10/2020
3	Neoplasms (Cancer) 11/2020 - 01/2010
2	Enterovirus Infections 02/2024 - 01/2022
2	Leptospirosis 01/2024 - 12/2022
2	Hypoxia (Hypoxemia) 10/2023 - 10/2023
2	Inflammation (Inflammations) 07/2023 - 11/2022
1	Cardiomegaly (Heart Hypertrophy) 04/2024
1	Fatty Liver 01/2024
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2024
1	Lung Neoplasms (Lung Cancer) 01/2023
1	Genetic Predisposition to Disease (Genetic Predisposition) 12/2022
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 11/2022
1	Demyelinating Diseases (Demyelinating Disease) 11/2022
1	Weight Loss (Weight Reduction) 11/2022
1	Bronchiolo-Alveolar Adenocarcinoma (Adenocarcinoma, Bronchiolo Alveolar) 01/2022
1	Body Weight (Weight, Body) 12/2020
1	Coinfection 04/2020
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2018
1	Hypersensitivity (Allergy) 01/2013
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2010

Drug/Important Bio-Agent (IBA)

6	Antiviral Agents (Antivirals)IBA 01/2024 - 01/2018
6	DNA (Deoxyribonucleic Acid)IBA 12/2019 - 02/2013
5	Proteins (Proteins, Gene)FDA Link 12/2023 - 01/2011
4	Metformin (Glucophage)FDA LinkGeneric 02/2024 - 01/2022
4	O- (5- O- (4- coumaroyl)- alpha- arabinofuranosyl)- (1- 3)- O- beta- xylopyranosyl- (1- 4)- xylopyranoseIBA 12/2020 - 01/2017
4	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 01/2019 - 02/2013
3	InterferonsIBA 01/2023 - 01/2021
3	EmetineIBA 01/2022 - 01/2020
3	Histones (Histone)IBA 12/2019 - 01/2011
3	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2019 - 01/2011
2	pleconarilIBA 02/2024 - 01/2022
2	rupintrivirIBA 02/2024 - 01/2022
2	remdesivirIBA 02/2024 - 01/2022
2	Drug CombinationsIBA 02/2024 - 04/2020
2	Messenger RNA (mRNA)IBA 02/2024 - 12/2023
2	Biomarkers (Surrogate Marker)IBA 01/2024 - 07/2023
2	Arginine (L-Arginine)FDA Link 10/2023 - 10/2023
2	3-(2,2,2-trimethylhydrazine)propionateIBA 10/2023 - 10/2023
2	Interferon-alpha (Interferon Alfa)IBA 01/2023 - 12/2021
2	CytokinesIBA 12/2022 - 11/2022
2	AnisomycinIBA 01/2022 - 10/2020
2	Cycloheximide (Cicloheximide)IBA 01/2022 - 10/2020
2	VemurafenibIBA 01/2022 - 10/2020
2	HomoharringtonineIBA 10/2020 - 01/2020
1	RNA (Ribonucleic Acid)IBA 04/2024
1	Histone Deacetylase InhibitorsIBA 04/2024
1	Neuraminidase (Sialidase)IBA 04/2024
1	theaflavinIBA 04/2024
1	Proton Pumps (Proton Pump)IBA 04/2024
1	nirmatrelvir and ritonavir drug combinationIBA 01/2024
1	CatecholaminesIBA 01/2024
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2024
1	AntibodiesIBA 12/2023
1	mRNA VaccinesIBA 12/2023
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2023
1	C-Reactive ProteinIBA 07/2023
1	Anti-Bacterial Agents (Antibiotics)IBA 06/2023
1	CrizotinibIBA 01/2023
1	brigatinibIBA 01/2023
1	entrectinibIBA 01/2023
1	alectinibIBA 01/2023
1	ceritinibIBA 01/2023
1	lorlatinibIBA 01/2023
1	Anaplastic Lymphoma KinaseIBA 01/2023
1	Protein Kinase InhibitorsIBA 01/2023
1	Transcription Factors (Transcription Factor)IBA 11/2022
1	Myelin-Oligodendrocyte GlycoproteinIBA 11/2022
1	Interleukin-17 (Interleukin 17)IBA 11/2022
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2022
1	Viral RNAIBA 12/2021
1	peginterferon alfa-2a (Pegasys)FDA Link 01/2021
1	nafamostatIBA 01/2021
1	SofosbuvirIBA 10/2020
1	Lamivudine (Epivir)FDA Link 10/2020
1	brequinarIBA 10/2020
1	Niclosamide FDA Link 10/2020
1	Tenofovir (Viread)FDA Link 10/2020
1	Monensin (Coban)IBA 10/2020
1	VaccinesIBA 04/2020
1	salinomycinIBA 01/2020
1	obatoclaxIBA 01/2020
1	Nelfinavir (Viracept)FDA Link 01/2020
1	Amodiaquine (Camoquin)FDA Link 01/2020
1	Protein Kinases (Protein Kinase)IBA 01/2019
1	DNA Ligases (Ligases, DNA)IBA 01/2017
1	Phosphotransferases (Kinase)IBA 02/2013
1	Histone MethyltransferasesIBA 01/2013
1	EnzymesIBA 01/2010

Therapy/Procedure

4	Therapeutics 06/2023 - 01/2010
2	Drug Therapy (Chemotherapy) 10/2023 - 01/2010
1	Fecal Microbiota Transplantation 12/2022
1	Oral Administration 11/2022
1	Radiotherapy 11/2020